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Minerva Cardioangiol ; 61(4): 377-91, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23846006

RESUMO

The scientific and technological progress in the field of medicine has allowed to treat patients with severe aortic valve stenosis and with a high perioperative risk. Before the introduction of transcatheter aortic valve implantation (TAVI), patients considered at high risk for surgical treatment were managed with medical therapy or with balloon aortic valvuloplasty. With more than 50000 transcatheter aortic valves implanted in patients around the world, TAVI has demonstrated to be a valid alternative to surgical aortic valve replacement in inoperable and high-risk patients. The PARTNER trial was the first randomized controlled trial to demonstrate that TAVI is not inferior to SAVR in high-risk patients. However, despite some encouraging short-term results medium and long-term outcomes are not always so encouraging. In this review, we will present the immediate results and distinct TAVI-related drawbacks and relative impact on the long-term outcome. New technology advances promise to simplify TAVI and to improve the results by reducing the rate of TAVI-specific issues such as paravalvular aortic regurgitation, annular rupture, and conduction disturbances which may impact on the clinical outcome. Therefore, we believe that when some of these weaknesses will be overcome, even patients at lower risk might benefit from TAVI in the near future.


Assuntos
Valva Aórtica/cirurgia , Cateterismo Cardíaco/estatística & dados numéricos , Procedimentos Endovasculares/estatística & dados numéricos , Implante de Prótese de Valva Cardíaca/estatística & dados numéricos , Insuficiência da Valva Aórtica/etiologia , Insuficiência da Valva Aórtica/cirurgia , Estenose da Valva Aórtica/cirurgia , Arritmias Cardíacas/etiologia , Cateterismo Cardíaco/mortalidade , Cateteres Cardíacos , Doenças Cardiovasculares/mortalidade , Desenho de Equipamento , Previsões , Ruptura Cardíaca/etiologia , Próteses Valvulares Cardíacas , Implante de Prótese de Valva Cardíaca/métodos , Implante de Prótese de Valva Cardíaca/mortalidade , Humanos , Complicações Intraoperatórias/etiologia , Estudos Multicêntricos como Assunto , Complicações Pós-Operatórias/etiologia , Ensaios Clínicos Controlados Aleatórios como Assunto , Recidiva , Acidente Vascular Cerebral/etiologia , Taxa de Sobrevida , Resultado do Tratamento
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